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GLP-1RA for the treatment of pediatric MASLD MASLD is highly prevalent in children and adolescents, with an estimated overall global prevalence of 7.4%, rising to 52.49% in the context of obesity

Fatigue Some people experience fatigue during the first few weeks of tirzepatide use, regardless of dose

Therefore, this review aims to synthesize the evidence on the mechanistic expansion of GLP-1RAs from metabolic regulators to systemic modulators of inflammation, autophagy, and organ protection, and explores their therapeutic repurposing across diseases

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Erythromycin antagonises the deceleration of gastric emptying by glucagon-like peptide 1 (GLP-1) and unmasks its insulinotropic effect in healthy subjects