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Description
DPP-4, dipeptidyl peptidase 4

2024 doi: 10.1124/pharmrev.123.001045
There were decreases in multiple lipid markers from baseline to 13 weeks among those receiving the study drug

Hwas UPenn colleagues, including Adam Vesole, MD, a neurotology fellow, are studying whether glucagon-like peptide-1 receptor agonists can play a therapeutic role in PT

A gut hormone that serves as a messenger with receptors all over the body, GLP-1 stimulates insulin levels and inhibits glucagon, a hormone that raises your blood sugar

So, for women who are following Hormone Replacement Therapy (HRT) by taking a pill, the decreased absorption of the drugs can actually cause a sudden (but unwanted) drop in estrogen causing mood swings and hot flashes to unexpectedly return
