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However, a more recent RCT of 255 adults with nicotine dependence did not show any effect of adjunctive dulaglutide compared with standard of care (that is, behavioral counseling with varenicline) on cigarette abstinence over 12 weeks of treatment 117

Personalized GLP-1 Selection with Genetic Testing Not every patient responds identically to semaglutide or tirzepatide because genetic variation affects how your body's appetite-regulating peptides function

[DOI] [PubMed] [Google Scholar] Xiao Q, Giguere J, Parisien M, Jeng W, St-Pierre SA, Brubaker PL, Wheeler MB

Lindegaard, M.D., D.M.Sc., Danil V

Scientists don't fully understand how these drugs work yet