glp-1 and depression Depression: Oranges, exercise, drugs tied to lower risk Psychotropic effects of GLP-1R agonists

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Certain medications also combine GLP-1 action with hormones like Tirzepatide, which work by targeting both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

Glucose-dependent insulinotropic polypeptide (GIP) Mol

Among 142 patients meeting inclusion criteria, 59.9 percent were documented as having improvement in HS after GLP-1RA use

A shift from weight loss to a broader cardiometabolic disease approach

From a mechanistic standpoint, this dual action explains why the same class can be used for both diabetes and weight management