glp 1 with cv benefit GLP-1 Agonists in Cardiovascular Diseases: Mechanisms, Clinical Evidence, and Emerging Therapies Mechanisms by which GLP-1 agonists
Description
Vomiting occurred for 69 patients on 5mg, 106 patients on 10mg, and 132 patients on 15mg
Cho SS, Qi L, Fahey Jr GC, Klurfeld DM
A human study showed that GLP-1 significantly delayed gastric emptying but did not affect gastric muscle contractility or water homeostasis, suggesting GLP-1 inhibits gastric emptying through an indirect mechanism rather than altering muscle contractility directly [121]
doi: 10.1111/j.1755-5922.2010.00256.x
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