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Large amounts without sufficient fluid will almost certainly make constipation worse

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In a study using rats with spinal nerve ligation, exenatide was found to reduce neuropathic pain, specifically by lowering sensitivity to touch (allodynia) [95-97]

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Several studies have linked insulin resistance to residual depressive symptoms, particularly anhedonia, fatigue, and cognitive slowing, which are often resistant to standard antidepressant treatments [19,63,64]

Mice received an IP injection (10 mg/kg) of Buprecare (Buprenorphine 0.3 mg