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A study published in Chimica Oggi - Chemistry Today by Berger et al

Prog Neurobiol 2002;68:377392.ArticlePubMed 17

Two decades later Joseph von Mering and Oscar Minkowski, two German physicians based at the University of Strasbourg, showed in a dog that the surgical removal of the pancreas, known as a pancreatomy, immediately caused severe and fatal diabetes

The Precision Peptide Genetic Test identifies genetic variants affecting GLP-1 sensitivity independent of age

10.14814/phy2.13852 65 RazI.FonsecaV.KipnesM.DurrwellL.HoekstraJ.BoldrinM.et al (2012)

They were used for diabetes for more than a decade before being approved for weight loss