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Visfatin is also involved in adipose tissue fibrosis promoting ECM protein production including Collagen type VI, MMP-2 and MMP-9 [190] (Fig

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Increased Energy and Mobility: As weight decreases, most individuals report increased energy levels and enhanced mobility, making it easier to engage in physical activities

Appetite suppression is expected, but when its too strong, it can contribute to nausea or low energy

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Some patients carry genetic variants that make them more sensitive to GLP-1 receptor activation, potentially amplifying heart rate effects