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NLRP3 inflammasome and inflammatory bowel disease

FDA labels specifically warn about this risk

Berberine Hydrochloride, a plant-derived compound found in several herbs, is widely known for AMPK pathways

She also had type 2 diabetes, so had been taking the GLP-1 inhibitor drug dulaglutide (Trulicity)

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Orforglipron Reduces Body Weight in HFD-Induced Humanized GLP-1R Mice B-hGLP1R mice plus were fed a high-fat diet (HFD) to induce obesity, followed by oral Orforglipron treatment