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The studies involved subjects, rather small numbers in each case, who had diabetes, non-alcoholic fatty liver disease (NAFLD), polycystic ovary syndrome (PCOS), coronary disease or had kidney transplants

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The dual incretin agonist tirzepatide reduced 24-hour ambulatory BP for adults with obesity-related hypertension, with the effects potentially independent of weight loss, according to data from a planned substudy of the SURMOUNT-1 trial.“Tirzepatide led to clinically meaningful reductions in ambulatory blood pressure among adults with overweight and obesity, with reductions in the range

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