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(2024) A long-acting glucose-dependent insulinotropic polypeptide receptor agonist improves the gastrointestinal tolerability of glucagon-like peptide-1 receptor agonist therapy

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As the field advances, humanized preclinical systems that allow drug evaluation against human targetssuch as GCGR/GIPR/GLP1R humanized mouse modelswill play a pivotal role in bridging the gap between mechanistic discovery and clinical translation

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Each case is unique, and factors such as a mother's metabolic health, nutritional status, and specific circumstances should be assessed

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