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Posttranslational processing of preproglucagon The vast majority of glucagon is produced in the pancreatic -cells, but, under some conditions, small amounts of glucagon also have been detected in the intestinal L-cells [87], although the validity of immunoassays to distinguish different proglucagon products has been questioned, and some reports were unable to find genuine glucagon in the intestine by mass spectrometric analysis [[144], [145], [146]]

P = 0.040), new-onset systolic heart failure (RRR: 26%, HR: 0.73

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If we are willing to step beyond traditional abstinence-based paradigms, GLP-1RAs may pave the way for a more inclusive, effective, and pragmatic approach to reducing alcohol-related harm