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Up to 40 to 50% of researchers report nausea during the first week at 8mg
Reddit threads and support groups are full of people describing feeling "flat" or "numb" going through the motions without feeling much of anything

Diabetes Care (2015) 38(12):22419

If you're using or considering any prescription weight-loss medication, mention any patches you're using too
doi: 10.1111/dom.13847

But I think theres going to be a real push in the system towards treating these people who what they are is not very sick