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Women of childbearing potential taking an oral hormonal contraceptive should add a barrier contraceptive for 4 weeks after starting tirzepatide and after each dose escalation

Some strains used in the study were provided by the Caenorhabditis Genetics Center, supported by NIH Office of Research Infrastructure Programs (P40 OD010440)

P., & STEP 5 Study Group

A constant infusion of fentanyl was used to ensure analgesia (5 g/kg/h)
