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Description
Several lines of evidence indicate that NAcc GLP-1R activation decreases food intake by reducing food palatability

However, off-label prescribing carries important considerations

doi: 10.1016/j.ejphar.2015.09.029 67 PajaresMRojo AIMandaGBoscLCuadradoA

[14] [39] In December 2025, the FDA approved an oral version of semaglutide for weight management, using the same brand name (Wegovy) as the injectable version

The FDA said it would not take enforcement action against compounders before the court ruled

More recently, rare cases of blindness in a small number of people have been reported
