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Both medications are metabolized primarily by your liver through cytochrome P450 pathways, but they use different enzyme familieshydroxyzine uses CYP3A4 and CYP2D6, while semaglutide undergoes hydrolysis and transaminase metabolism

Myasthenic symptoms often worsen during pregnancy, most commonly during the first trimester

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Month 3+: The full range of benefits, including significant weight loss and improved metabolic markers, usually become noticeable

The data look particularly strong, and should push the program back into investor conversations, Cantor Fitzgerald analyst Prakhar Agrawal wrote in a note to investors

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