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The application requires a safety assessment covering toxicity, allergenicity and dietary exposure

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This narrative review aims to explore the role of GLP-1 RAs in weight management and cardiovascular health, and how they affect metabolic parameters such as blood glucose, lipid profiles, and blood pressure

Conclusions This realworld analysis of a large US claims database shows semaglutide was associated with early and significantly greater reductions in the risk of rMACE3 and rMACE5 versus tirzepatide among patients with overweight or obesity and ASCVD but without diabetes