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Furthermore, in a more physiological setting, CCK-1R antagonism during a fasting-refeeding paradigm results in hyperglycemia, highlighting the glucoregulatory relevance of CCK-8 signaling 194

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Five registered trials, Phase 3 program (Enith1, Enith2) underway

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As obesity is a complex, chronic and progressive disease, it requires also an individualised and adaptive over time approach [14, 102]

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monotherapies [118, 119]

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For behavioral studies, data were analyzed by ANCOVA, or repeated-measures one-way or two-way ANOVA followed by Tukeys or Bonferronis post hoc test as appropriate

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