mapping the effectiveness and risks of glp-1 receptor agonists pdf agonism: a transformative approach for managing type-2 diabetes obesity The expanding scope of GLP-1

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GLP-1RAs vs metformin (ancillary analysis) Several studies have shown that metformin may correct components of the metabolic syndrome [23]

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1416 Beyond compositional shifts, the functional consequences of dysbiosis are particularly relevant: the microbiota contributes to obesity pathophysiology by driving the production of short-chain fatty acids (SCFAs), modulating bile acid metabolism, and influencing immune and inflammatory pathways