glp-1 drug news today Alarming rise in weight loss overdoses Swiss Re says GLP-1 drugs
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While many drugs in this class were initially approved to treat type 2 diabetes, they have also been approved for weight loss

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All of the dynamics around GLP-1s, compounding shortage workarounds, and potential for DTC telehealth fallout I described last August seem to be playing out in 2025

Ozempic is the brand name for an injectable form of semaglutide thats approved for treating type 2 diabetes

But this boom has a cost
I think most people think about these processes in terms of a single, ideal bound conformation of the peptide to the receptor as the basis for signalling, says Gellman, but Im increasingly suspecting that certain modes of dynamics are critical for signalling. He is now trying to design this structural variability into his hybridtides to see if this will improve on the performance of GLP-1 drugs
