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In hormone therapy, the main job is to tell your body to make more human growth hormone

Some patients report increased redness, swelling, or discomfort at injection sites when using compounded semaglutide with b12 compared to brand-name semaglutide alone

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10.1016/j.nefro.2022.07.008 [DOI] [PubMed] [Google Scholar] 27
If aches dont subside after the initial adjustment period, reach out to your provider
The answer depends on whether the less effective medication still crosses the therapeutic threshold