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Before stopping, talk with your prescriber about: whether dose reduction is appropriate how often to monitor weight how to respond to early regain what nutrition structure should be in place how to maintain protein and resistance training what other treatment options may be appropriate Do not stop suddenly without medical guidance, especially if you are using the medication for type 2 diabetes

After 26 weeks, tesofensine showed significant weight loss and potentially higher weight reduction compared to existing anti-obesity medications

The ITP-LNPs were measured for size with a Zeta Sizer Nano Series (ZEN3600, Malvern, UK) and transmission electron microscopy images were obtained with a Hitachi Ht 7800 TEM instrument (Hitachi, Tokyo, Japan)

Your healthcare team can adjust your dosing schedule or pause treatment temporarily while you manage acute symptoms, then resume once you're eating normally again

Factors beyond genetics also shape outcomes: starting weight, baseline metabolic rate, diet adherence, physical activity level, sleep quality, and stress management all contribute to final results