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Supplementary Materials Data Availability Statement The raw data supporting the conclusions of this article will be made available by the authors on request.

A practical data point to hold: a field summary from FN Personal Trainers found that overeating on Ozempic can lead to a 30% increase in gastrointestinal discomfort, which tracks with the symptom clustering we observe in side-effect logs and follow-ups

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Based on previous studies done in mice, researchers observed that GLP-1 agonists/DPP-4 inhibitors work to reduce inflammation in the gut, so they proposed that the same mechanism may occur in humans (5, 6)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 759.Navarro M., Rodriquez de Fonseca F., Alvarez E., Chowen J.A., Zueco J.A., Gomez R