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NauckMAHombergerESiegelEGAllenRCEatonRPEbertRet al

Bioelectric neuromodulation might be a valuable treatment for several gastrointestinal disorders but further investigations into the underlying mechanisms, placement of stimulating electrodes, stimulus parameters and patient populations to optimize effectiveness are still required

The median (IQR) number of patients across studies was 355 (1295)

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Some men see minimal change while others notice immediate effects

Several preclinical models and clinical studies also suggest their potential as a novel therapeutic strategy for managing pain symptoms