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Description

If blood pressure decreases due to weight loss and improved metabolic health, existing blood pressure medications may need adjustment to prevent hypotension (excessively low blood pressure)

Clinical studies exploring microbiological endpoints, metagenomic analysis, and functional tests are needed

If you want a broader overview of that hormone and its role in weight loss, our guide on what GLP-1 is and how it works is a helpful place to start

Healthcare providers should assess for: Persistent gastrointestinal symptoms that may indicate gallbladder disease Signs of pancreatitis (severe abdominal pain radiating to the back) Changes in vision or symptoms of diabetic retinopathy progression, especially in patients with pre-existing retinopathy Signs of dehydration or acute kidney injury with severe gastrointestinal symptoms Hypoglycemia when used with insulin or sulfonylureas (which may require dose reduction of these medications) Symptoms related to the boxed warning (thyroid tumors): neck mass, hoarseness, dysphagia, or dyspnea Patients should be aware that semaglutide is contraindicated during pregnancy and lactation, and women of childbearing potential should stop treatment approximately 2 months before a planned pregnancy