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Numerous studies have highlighted the distinctive benefits of GLP-1 RAs in diabetes management, showcasing a reduced risk of hypoglycemia, the capacity to restore -cell function, and the potential to enhance cardiovascular outcomes, particularly in high-risk populations (4, 5)

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2015;62:S25S37

Case 2: Due to a national shortage of 1.0 mg semaglutide, a female whose weight was previously stable on phentermine 15mg/topiramate 25mg twice daily plus GLP-1 agonist therapy (i.e., semaglutide) was switched to 5mg tirzepatide in-between clinic visits

Some are now also FDA-approved for chronic weight management
