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Stein MS, Kalff V, Williams SG, Murphy DG, Colman PG, Hofman MS

Berberine also directly influences fat metabolism, acting as an anti-adipogenic agent by suppressing the regulation of transcription factors vital for fat tissue growth, such as peroxisome proliferator-activated receptor gamma (PPARG), CCAAT enhancer binding protein (C/EBP), and sterol response element binding protein-1c (SREBP-1c) (AR

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Patients with diabetic retinopathy or proliferative changes require close ophthalmologic monitoring during treatment

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