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A study in Biochimie found that curcumin stimulates GLP-1 secretion from intestinal L-cells through an oxidation-dependent mechanism

These bold experiments are offering an early glimpse of how the medications might work in real-world clinical settings

Trade-off : Higher discontinuation rates (18.2% high dose vs

N Engl J Med 375(4):31122 [DOI] [PMC free article] [PubMed] [Google Scholar] 27.Gerstein HC, Colhoun HM, Dagenais GR (2019) Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomized placebo-controlled trial

Several clinical trials evaluated the use of GLP-1 receptor agonists in the treatment of solid organ post-transplant diabetes

Tirzepatide Introduced in 2022 under the brand name Mounjaro, Tirzepatide is a medication that combines the effects of GIP (Glucose-Dependent Insulinotropic Polypeptide) and GLP-1 receptor agonists