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New medicines that mimic a natural gut hormone called GLP-1 have already changed how clinicians treat type 2 diabetes, obesity and related cardiometabolic consequences

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Extrapolating from animal research to human effects requires significant caution, as metabolic pathways don't always translate directly between species

2024;13(1):e032277

Authors have concluded that the excitement surrounding DPP-4 inhibitors is justified because in addition to controlling blood glucose level, they are good at managing risk factors associated with diabetes