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In adults with obesity or overweight with 1 weight-related comorbidity, along with diet and exercise, A well-studied safety profile: Pooled safety data from 3 weight-management clinical trials evaluating Wegovy 2.4 mg pen 1 6.8% of patients treated with Wegovy and 3.2% of patients treated with placebo permanently discontinued treatment as a result of adverse reactions 1 Permanent discontinuation of treatment as a result of a gastrointestinal adverse reaction occurred in 4.3% of patients treated with Wegovy vs 0.7% of patients treated with placebo 1 The most common adverse reactions leading to discontinuation were: Nausea (1.8% vs 0.2%) , vomiting (1.2% vs 0%) , and diarrhea (0.7% vs 0.1%) for Wegovy and placebo, respectively 2 *Includes abdominal pain, abdominal pain upper, abdominal pain lower, gastrointestinal pain, abdominal tenderness, abdominal discomfort, and epigastric discomfort

Novo Nordisk, the producer of GLP-1 drug Ozempic, has also filed lawsuits in almost 40 states

Durable responses could potentially i) improve tolerability by limiting drug exposure ii) facilitate convenient dosing schedules and increased patient adherence and iii) lead to lower long term costs on our healthcare system/payers

Is Your Metabolism Really Broken

2020-2025 Dietary Guidelines for Americans
