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A recently published analysis conducted from a US third-party payer perspective also supported the results [25]

Importantly, semaglutide carries a boxed warning for risk of thyroid C-cell tumors, and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Ozempic and Mounjaro are FDA-approved to treat type 2 diabetes, not obesity, although they are sometimes prescribed off-label for weight loss

Zepbound: Designated as a weight loss treatment for adults with obesity or who are overweight with related health conditions, and for moderate to severe obstructive sleep apnea (OSA)

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