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549 The reactive astrocytes can promote excitotoxic injury of motor neurons by producing nitric oxide and peroxynitrite, which cause mitochondrial damage and apoptosis in cultured neurons, decreasing glutamate transport, releasing pro-apoptotic mediators selectively toxic to motor neurons

Effect of glucagon-like peptide-1 receptor agonists on vascular risk factors among adults with type 2 diabetes and established atherosclerotic cardiovascular disease

Chin Med J (Engl) 2008;121:21342138

Building Long-Term Fitness Success While on GLP-1 Medication After 612 weeks on GLP-1 therapy, most patients return to their pre-medication fitness level or exceed it

However, both glycemia and insulinemia did not show such a clear response to sitagliptin treatment, leading the authors themselves to raise doubts about this drug value in DM cats treatment (Nishii et al., 2014)

That range might seem wide