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Pancreatitis is a serious medical condition involving inflammation of the pancreas that can require hospitalization

When tirzepatide binds to GLP-1 receptors in the brain, particularly in the hypothalamus and brainstem, it sends powerful satiety signals

[1] Clinical trials demonstrate that most patients experience substantial weight reduction, with the rate of loss typically slowing as treatment continues

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Many of these side effects come from how the drug affects the stomach, digestion, and blood sugar levels