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In the TgCRND8 AD mouse model expressing the human APP gene, increased expression of IGFBP5 in A plaques and the surrounding areas of the hippocampus and deep cortex has been demonstrated [163]

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Semaglutide causes gastrointestinal side effects in a significant percentage of users

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These drugs have raised concerns due to their prescription for treating type 2 diabetes, which increases the risk of pancreatic cancer

Clinical trials assessing Wegovys effectiveness typically measure outcomes after 68 weeks of treatment, reflecting its role as a long-term therapy