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Medicare plans can now cover Wegovy for patients at risk of heart disease

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The FDA requires a black box warning about seizure risk (higher with high-fat meals, alcohol, or abrupt alcohol withdrawal) and about neuropsychiatric effects from bupropion including changes in mood, behavior, or suicidal thoughts

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(It held up in both Black and White women, too.) Now 30% less sounds dramatic, but the absolute number is calmer: about seven fewer breast cancers per thousand women

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GLP-1s will continue to disappoint unless we target the computational failure mode John Crary not only is AD (the biology) a complex multifactorial process, so is dementia the clinical syndrome

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