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Visual loss and optic neuropathy associated with Wernicke's encephalopathy in hyperemesis gravidarum

doi: 10.1210/endo.130.1.1309325

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Side Effects and Safety Profiles Because both forms contain semaglutide, their side-effect profiles are largely similar, such as: Nausea Vomiting Diarrhea Constipation These effects are typically dose-related and most noticeable during early treatment or dose increases

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Combination biology is full of cases where two drugs that look additive in a slice preparation deliver less in vivo, or deliver too much of the wrong thing in this case, too much nausea, since the area postrema is also the seat of GLP-1-induced anorexia and emesis