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Heerspink HJL, Sattar N, Pavo I, Haupt A, Duffin KL, Yang Z, Wiese RJ, Tuttle KR, Cherney DZI

The studys primary outcomes of interest (monitored over a 10-month follow-up period) included changes from baseline in Body Mass Index (BMI), AUDIT scores, and qualitative reports of cravings

On 4 June 2021, the FDA approved semaglutide injections (2.4 mg/week) for weight management in obese patients 30 kg/m 2 BMI or overweight patients 27 kg/m 2 BMI with at least one weight-related condition, including high blood pressure, T2DM or hypercholesterolemia [139]
The TRIUMPH-4 trial revealed a notable incidence of dysesthesia, an abnormal sensation affecting touch perception that can cause numbness, tingling, or unusual skin sensitivity

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Changes in mood, energy, or cognitive function that coincide with starting therapy
