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NICE guidance (NG28) recommends considering GLP-1 receptor agonists for adults with type 2 diabetes when glycaemic targets are not achieved with other therapies, particularly in those with established cardiovascular disease or at high cardiovascular risk

Understanding its effects establishes the baseline against which all subsequent escalations are measured

In chow-fed lean mice, P5 or Ex4 dosed at 1 g kg 1 significantly increased the level of insulin compared with control mice (Fig

Kobayashi H, Hosono O, Mimori T, Kawasaki H, Dang NH, Tanaka H, Morimoto C, et al

Int J Exp Diabetes Res 2001

McClean, P
