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Semaglutide works by reducing hunger and slowing stomach emptying, but certain foods can trigger nausea, vomiting, or diminish treatment effectiveness
There was a reduced relative and absolute risk of MACE for semaglutide vs comparators across the entire continuum of CV risk
Regarding renal effects, the evidence of SGLT2is in preventing kidney failure is more abundant than for GLP-1RAs, which showed a beneficial effect on albuminuria but not on hard kidney endpoints
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