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When prescribed and monitored by a licensed healthcare provider, these therapies may help support healthy metabolic function and appetite regulation in some individuals

Native GLP-1 has no use therapeutically, but the advent of GLP-1R agonists that have much longer half-lives has enabled GLP-1based actions for therapeutic uses as a viable option 57 )

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Heres how different groups responded to treatment: Race and Ethnicity : Clinical benefits were consistent across all racial and ethnic groups Type 2 Diabetes : Patients without diabetes achieved higher total body weight loss (16.9%) versus those with diabetes (9.9%) at 12 months Body Mass Index (BMI) : After two years of treatment, 52.4% of participants moved down at least one BMI category Results show that 12% of adults receiving semaglutide reached a healthy BMI of 25 kg/m or less, compared to only 1.2% in the placebo group

The current pricing window post-FDA reclassification, pre-TRIUMPH-1 demand wave is historically favorable