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Tocher, Zeling Lin, Bing Chen, Ruixin Li, Shuqi Wang, Cuiying Chen, Houguo Xu Aquaculture Nutrition.2025;[Epub] CrossRef Geranylgeranyl Pyrophosphate Promotes Hepatic Lipid Accumulation by Prenylation of Perilipin4 Yue Zhao, Hong-Yu Nie, Shan Jiang, Meng-Fei Zhao, Peng Sun, Jing-Zi Zhang, Xiao-Chen Wang, Yi-Ping Tang, Ming-jie Zou, Xian-Wen Yuan, Xi-Tai Sun, Xiao-Dong Shan, Jian He, Jiang-Huai Liu, Yan Bi, Lei Fang, Xiao Han, Chao-Jun Li Cellular and Molecular Gastroenterology and Hepatology.2025

References Paccou, J

Two deaths were reported in the triplet group, though its unclear if they were treatment-related

It remains unapproved for human use at time of writing (April 2026)

Some patients plateau temporarily between months 2 and 4 as their body adapts, which does not indicate treatment failure but rather a normal metabolic adjustment phase