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To mark 50 years of monoclonal antibodies, this Review from Chan, Martyn and Carter provides an overview of how antibody engineering strategies have continued to improve antibody-based therapeutics, chiefly focusing on antibody-mediated targeting of B cells and also human epidermal growth factor receptor 2 (HER2)+ cancers

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Even when patients use popular anti-obesity drugs with strong weight-loss effects, they can still reach a plateau where further weight loss stops

Quantitative mapping of the brains metabolism is a critical tool in studying and diagnosing many conditions, from obesity to neurodegenerative diseases