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Levodopa in Parkinsons disease: current status and future developments

With this impressive albeit still hypothetical set of benefits, Johnsons experiment makes sense

Other ERG assumptions included a natural weight increase of 0.30 kg per year compared to 0.46 kg, weight no longer increased after age 66 compared to age 68, natural weight decreased by 0.30 kg after age 66 compared to remaining constant, and the annual cost of sleep apnoea was 274 compared to 1081

This can be one of the more difficult side effects to overcome, especially early in treatment

Excipients are usually in much greater amounts than the API and can typically make up to ~90% of the entire drug product

Avoid dehydration - drink enough throughout the day
