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Obesity and metabolic conditions are among the most urgent health challenges worldwide , affecting over one-third of adults and contributing to diabetes, heart disease, and fatty liver disease
Novo Nordisk shares drop as Alzheimers hopes for weight-loss drug fade Novo Nordisks semaglutide failed to slow Alzheimers in large trials, prompting shares to fall and expert reactions.

Clinical trials have shown tirzepatide may produce greater weight loss on average
The starting dose in the standard published protocol is 2mg
doi: 10.2337/dc15-0843

Discovery of the once-weekly glucagon-like peptide-1 (GLP-1) analogue Semaglutide
