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At 24 weeks, liver-fat content (measured by non-invasive imaging, MRI-PDFF) fell by 81.4% on 8 mg and 82.4% on 12 mg, compared with a small increase in those participants on the placebo

[DOI] [PubMed] [Google Scholar] 211.Morgan-Bathke M., Raynor H.A., Baxter S.D., Halliday T.M., Lynch A., Malik N., Garay J.L., Rozga M

AnholmCKumarathuraiPSamkaniAPedersenLRBostonRCNielsenOWet alEffect of liraglutide on estimates of lipolysis and lipid oxidation in obese patients with stable coronary artery disease and newly diagnosed type 2 diabetes: a randomized trial

40 , 658674 (2007) Murshudov, G

The drug has a long half-life, which means it can be administered monthly or less frequently, giving the drug the potential to improve adherence and long-term weight control, according to Jay Bradner, executive vice president of research and development at Amgen