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Randomization was stratified according to country, sex (female, male) and per cent weight reduction at the end of lead-in ( 90% to demonstrate the superiority of tirzepatide MTD to placebo, for the coprimary endpoints, each at a two-sided significance level of 0.05

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doi: 10.1210/clinem/dgab848 [DOI] [PMC free article] [PubMed] [Google Scholar] 21
