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Cardiometabolic benefits are similar to injectable medications with decreases in lipids, blood pressure, hsCRP, and glucose

Semaglutide Phase 2 Trial: 59% NASH resolution at 0.4 mg/day Building upon the foundation established by the LEAN trial, researchers subsequently conducted a larger phase 2 trial evaluating semaglutides efficacy in NASH patients

(2018), showed that it is not possible to conclude whether DPP-4 inhibitors were associated with an increased risk of site-specific cancer including TC

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Best Cheap GLP-1 Receptor Agonist: Semaglutide or Tirzepatide

In a 2023 systematic review of the effectiveness of several obesity medications, semaglutide achieved the greatest mean weight loss, a finding that was echoed in a 2022 JAMA paper comparing semaglutide with liraglutide (figure 4) .* There is evidence to suggest that tirzepatide, currently approved for use as a diabetes medication but not yet as a weight loss drug, is superior still to semaglutide