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Day-to-day weight can vary by 2 to 4 pounds based on hydration, sodium intake, bowel contents, and hormonal cycles

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This can cause an uncomfortable feeling of fullness, tightness, or swelling in the abdomen

doi: 10.1016/j.mce.2015.07.003

Gentle next step If youre unsure whether your weight-loss pace is normal or which option fits your goals clinician guidance can help set expectations and prevent early burnout

Understanding tirzepatide with B12 Some providers may prescribe tirzepatide with vitamin B12 to possibly help reduce fatigue, support nerve function, and prevent vitamin B12 deficiency that may occur with long-term use of GLP-1 medications