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DPP-4 inhibitors were introduced for the treatment of type 2 diabetes in 2006

2C to 8C (36F to 46F)

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By Gabe Sanders PhD, NSCA-CSCS These medications were originally developed to treat Type 2 diabetes, but they are now widely used to support weight loss

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Here, we unveil the detrimental effect of a high cholesterol diet on GLP-1R-dependent glucoregulation in vivo , and the improvement in GLP-1R function that a reduction in cholesterol synthesis using simvastatin exerts in pancreatic islets