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Constipation affects a meaningful percentage of tirzepatide users at all doses

Understanding when to resume after surgery and how long before surgery to pause the compound is critical for safety

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Dickerson F, Stallings C, Origoni A, Vaughan C, Khushalani S, Yolken R

If a person on tirzepatide develops any of these gastrointestinal complications, they need immediate hospitalization and emergency medical care

Some research suggests the proportion may actually be slightly lower than with very-low-calorie diets
